Chronic inflammatory diseases are the most significant cause of death in the world. The World Health Organization (WHO) ranks chronic diseases as the greatest threat to human health.

In recent estimates by Rand Corporation, in 2014 nearly 60% of Americans had at least one chronic condition, 42% had more than one, and 12% of adults had 5 or more chronic conditions.

Worldwide, 3 of 5 people die due to chronic inflammatory diseases like stroke, chronic respiratory diseases, heart disorders, cancer, obesity, and diabetes.

The prevalence of some specific chronic inflammation-mediated diseases are as follows: 

Diabetes: According to the American Diabetes Association, 30.3 million people, or 9.4% of the American population, had diabetes in 2015. 

Cardiovascular diseases: Globally, CVD accounts for nearly a third (31%) of all deaths.

Arthritis and Joint Diseases: These affect approximately 350 million people worldwide.

Allergies: These rank among the sixth leading cause of chronic human diseases in the United States and affect more than 50 million Americans each year. Asthma affects more than 24 million people in the United States including more than 6 million children. In 2015, 8.2% of adults and 8.4% of children were diagnosed with hay fever. 

Chronic Obstructive Pulmonary Disease (COPD): The third most common cause of death in the United States in 2014, and nearly 15.7 million Americans (6.4%) were reported to have been diagnosed with COPD